2017 was a career year for Melvin. This was his fourth season on an NFL roster, and he made the most of it. While he missed six games due to injuries, he still established himself as the top member of the Colts’ secondary as he logged a career-high 3 interceptions.
In a Week 7 loss to the Jaguars, he suffered a concussion that cost him most of that game and all of Week 8. After returning in Week 9, he was able to play until Week 11. Melvin started that loss to the Titans before suffering a hand injury after making an interception.